Podcast
The a16z Show
Andreessen Horowitz
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
— All episodes
EPISODES
- 01
Mar 9, 2026 · 51m E1051
Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity
Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They dis...
- 02
Mar 6, 2026 · 55m E1050
Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next
Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all soft...
- 03
Mar 5, 2026 · 36m E1048
Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power
In this conversation, previously aired on TBPN, John Coogan and Jordi Hays speak with Ben Thompson, founder of Stratechery, about his essay "Anthropic and Al...
- 04
Mar 4, 2026 · 49m E1049
Ambience CEO Nikhil Buduma on AI in Clinical Workflows
a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They...
- 05
Mar 3, 2026 · 50m E1047
Ben Horowitz On What Makes a Great Founder
On the show Long Strange Trip, Sequoia Capital partner Brian Halligan speaks with a16z’s Ben Horowitz about what separates great founder CEOs from everyone e...
- 06
Mar 2, 2026 · 59m E1046
Chris Dixon: From Quant Trading to Building a16z Crypto
In this feed drop from the Internet History Podcast, host Brian McCullough speaks with Chris Dixon, general partner at a16z, about his path from 1980s hobbyi...
- 07
Feb 27, 2026 · 48m E1045
a16z's New Media Playbook
Erik Torenberg, Ben Horowitz, and Marc Andreessen discuss how the media landscape has fundamentally changed and what a16z is doing about it. They cover why o...
- 08
Feb 26, 2026 · 47m E1044
When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market
Bloomberg's Odd Lots hosts Joe Weisenthal and Tracy Alloway speak with David George, general partner at a16z and head of the firm's growth fund, about why $5...
- 09
Feb 23, 2026 · 1h 48m E1043
Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics
Moonshots host Peter Diamandis speaks with Ben Horowitz, cofounder and general partner at a16z, alongside regular cohosts Salim Ismail, Dave Blundin, and Dr....
- 10
Feb 20, 2026 · 52m E1042
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding
Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk a...
- 11
Feb 19, 2026 · 57m E1041
Capital, Compute, and the Fight for AI Dominance
a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the hi...
- 12
Feb 18, 2026 · 59m E1040
From Copilots to Agents: Rebuilding the Company Around AI
a16z's Angela Strange and Gabriel Vasquez speak with Carlos García Ottati, founder and CEO of Kavak, about building Latin America's largest online used car m...
- 13
Feb 17, 2026 · 30m E1039
WSJ x a16z: The Next 25 Years of Defense Innovation
In this episode from WSJ Invest Live, Andy Serwer speaks with Katherine Boyle, general partner at a16z, about the American Dynamism practice she helped launc...
- 14
Feb 16, 2026 · 58m E1038
Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company
a16z general partner Jorge Conde talks with Vasant Narasimhan, CEO of Novartis International, about transforming a 250-year-old conglomerate into a pure play...
- 15
Feb 13, 2026 · 1h 3m E1037
Balaji and Dan Wang: The Engineering State vs Lawyerly State
Balaji Srinivasan speaks with Dan Wang, author of Breakneck, about China's industrial rise, America's competing strengths in software and finance, and what h...
- 16
Feb 12, 2026 · 1h 21m E1036
Anish Acharya: Is SaaS Dead in a World of AI?
In this episode from 20VC, Harry Stebbings talks with Anish Acharya, general partner at a16z, about the future of SaaS in an AI world. Anish argues that soft...
- 17
Feb 11, 2026 · 1h 5m E1035
How Magic Johnson Built a Billion-Dollar Portfolio in 30 Years
a16z’s Chris Lyons speaks with Earvin "Magic" Johnson about his 30-year journey from athlete to billionaire businessman. They cover the art of deal-making, l...
- 18
Feb 10, 2026 · 26m E1034
Marc Andreessen: Who Runs the World’s AI?
Cisco president and CPO Jeetu Patel speaks with a16z cofounder Marc Andreessen about why AI may finally break a 50-year productivity slump—and what's at stak...
- 19
Feb 9, 2026 · 47m E1033
The State of Markets
a16z Head of Investor Relations Jen Kha speaks with general partner David George about the state of AI and private technology markets. David shares data on w...
- 20
Feb 6, 2026 · 2h 6m E1032
Balaji & Benedict Evans: When Tech Breaks Industries
This episode originally appeared on the Network State Podcast. Balaji Srinivasan and Benedict Evans sit down in Singapore for a wide-ranging conversation on...
- 21
Feb 5, 2026 · 29m E1031
Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES
Christopher Mims and Tim Higgins of the Wall Street Journal sit down with a16z General Partner Martin Casado on WSJ’s Bold Names to ask whether the AI spendi...
- 22
Feb 4, 2026 · 41m E1030
Why America’s Health Crisis Is an Incentive Problem
a16z general partner Erik Torenberg speaks with Justin Mares, founder and CEO of TrueMed. They discuss why American health outcomes are so poor compared to t...
- 23
Feb 3, 2026 · 1h 2m E1029
Palmer Luckey on Hardware, Building, and the Next Frontiers of Innovation
Recorded live at our Founders Summit, a16z general partner Chris Dixon speaks with Palmer Luckey, founder of Anduril and Oculus VR. They talk about what it t...
- 24
Feb 2, 2026 · 36m E1028
David Solomon & Ben Horowitz on Building Organizational Resilience & Navigating Macro Uncertainty
a16z general partner David Haber spoke with Goldman Sachs CEO David Solomon and a16z cofounder Ben Horowitz on the current macro environment, enterprise AI a...
- 25
Jan 30, 2026 · 57m E1019
“Anyone Can Code Now” - Netlify CEO Talks AI Agents
Netlify's CEO, Matt Biilmann, reveals a seismic shift nobody saw coming: 16,000 daily signups—five times last year's rate—and 96% aren't coming from AI codin...
- 26
Jan 29, 2026 · 1h 41m E1027
Marc Andreessen on Why This Is the Most Important Moment in Tech History
Recently, Marc Andreessen joined Lenny Rachitsky on Lenny's Podcast. They talked about why 2025 may be the most significant year in tech history, how AI is r...
- 27
Jan 28, 2026 · 42m E1026
Ben Horowitz and Balaji Srinivasan on Netscape and Network States
Can a country be built from the internet up? Not as a metaphor or an online community, but as a system that replaces institutions we usually think of as fixe...
- 28
Jan 27, 2026 · 1h 34m E1024
Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection
Out-of-Pocket is a healthcare education company founded by Nikhil Krishnan that helps people understand how healthcare works and how to navigate it in practi...
- 29
Jan 26, 2026 · 1h 4m E1023
The Hidden Economics Powering AI
In this episode, Jen Kha, Head of Investor Relations, and David George, General Partner, discuss how late-stage private markets are evolving as AI reshapes s...
- 30
Jan 23, 2026 · 44m E1022
How Mintlify Is Rebuilding Documentation for Coding Agents
Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreess...
- 31
Jan 22, 2026 · 43m E1021
Inferact: Building the Infrastructure That Runs Modern AI
Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference...
- 32
Jan 21, 2026 · 27m E1020
Martin Casado on the Demand Forces Behind AI
In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing....
- 33
Jan 20, 2026 · 46m E1018
From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu
Sourcegraph's CTO just revealed why 90% of his code now comes from agents—and why the Chinese models powering America's AI future should terrify Washington....
- 34
Jan 19, 2026 · 1h 10m E1013
The AI Opportunity That Goes Beyond Models
The a16z AI Apps team outlines how they are thinking about the AI application cycle and why they believe it represents the largest and fastest product shift...
- 35
Jan 16, 2026 · 57m E1016
How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era
The Stanford PhD who built DSPy thought he was just creating better prompts—until he realized he'd accidentally invented a new paradigm that makes LLMs actua...
- 36
Jan 15, 2026 · 58m E1015
Ben & Marc: Why Everything Is About to Get 10x Bigger
a16z cofounders Marc Andreessen and Ben Horowitz join a16z general partner Erik Torenberg and Not Boring founder Packy McCormick for a conversation on how th...
- 37
Jan 14, 2026 · 17m E1014
Alex Rampell on TBPN: Revenge, Redemption, and Founder Drive
a16z General Partner Alex Rampell joined the Technology Brothers Podcast Network following the announcement of Andreessen Horowitz’s new fund to discuss what...
- 38
Jan 13, 2026 · 34m E1009
Ben Horowitz on Investing in AI: AI Bubbles, Economic Impact, and VC Acceleration
AI is changing how companies are built and how venture firms operate, forcing faster decisions, clearer judgment, and new ways of working. In this exclusive...
- 39
Jan 12, 2026 · 1h 11m E1012
Alex Rampell on Venture at Scale and Founder Incentives
This episode is a special feed drop from The Twenty Minute VC, featuring a conversation between Harry Stebbings and a16z General Partner Alex Rampell. Alex s...
- 40
Jan 11, 2026 · 24m E1011
Ben Horowitz on TBPN: Three Decades with Marc and Building for the Long Game
Following the announcement of a16z’s new fund, Andreessen Horowitz cofounder and general partner Ben Horowitz joined TBPN to discuss how Andreessen Horowitz...
- 41
Jan 9, 2026 · 59m E1010
Ben Horowitz on Raising a New Fund and How Venture Firms Scale
In this feed drop from Uncapped, Jack Altman sits down with a16z co-founder Ben Horowitz to unpack the founding bet behind Andreessen Horowitz. VC should be...
- 42
Jan 8, 2026 · 32m E1008
Keycard: 2026 is the Year of Agents
In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Key...
- 43
Jan 7, 2026 · 1h 21m E1007
Marc Andreessen's 2026 Outlook: AI Timelines, US vs. China, and The Price of AI
a16z co-founder and General Partner Marc Andreessen joins an AMA-style conversation to explain why AI is the largest technology shift he has experienced, how...
- 44
Jan 6, 2026 · 58m E1006
Figma’s Dylan Field on the Future of Design
Dylan Field is the co-founder and CEO of Figma, a design software company that went public in July 2025. Founded in 2012, Figma transformed how people design...
- 45
Jan 5, 2026 · 1h 3m E1005
AI Will Save The World with Marc Andreessen and Martin Casado
Originally published in June 2023, this conversation features a16z cofounder Marc Andreessen following the release of his nearly 7,000-word essay arguing tha...
- 46
Jan 2, 2026 · 35m E1004
Wartime vs Peacetime: Ben Horowitz on Leadership
In this exclusive conversation from a16z’s Bio and Health BUILD Summit, founding partner Ben Horowitz sits down with general partner Jorge Conde. Originally...
- 47
Jan 1, 2026 · 1h 6m E1003
The Techno-Optimist Manifesto with Marc Andreessen and Ben Horowitz
Originally aired in October 2023, this episode centers on Marc Andreessen’s essay The Techno-Optimist Manifesto, which lays out his vision for the future of...
- 48
Dec 31, 2025 · 28m E989
The Inside Story of Growth Investing at a16z
This episode is a special replay of David George’s conversation with Harry Stebbings on 20VC. David is a General Partner on a16z’s growth team, and in this d...
- 49
Dec 30, 2025 · 1h 22m E1002
Why a16z's Martin Casado Believes the AI Boom Still Has Years to Run
This episode is a special replay from The Generalist Podcast, featuring a conversation with a16z General Partner Martin Casado. Martin has lived through mult...
- 50
Dec 29, 2025 · 44m E1001
Where Does Consumer AI Stand at the End of 2025?
As 2025 comes to a close, consumer AI is entering a new phase. A small number of products now dominate everyday use, multimodal models have unlocked entirely...
- 51
Dec 26, 2025 · 20m E1000
Big Ideas 2026: New Infrastructure Primitives
New infrastructure primitives are creating entirely new rails for building. In this episode of Big Ideas 2026, we explore three foundational shifts that unlo...
- 52
Dec 25, 2025 · 21m E999
Big Ideas 2026: Physical AI and the Industrial Stack
AI is moving into the physical economy. In this episode of Big Ideas 2026, we explore what changes when AI leaves the screen and becomes part of factories, c...
- 53
Dec 24, 2025 · 17m E998
Big Ideas 2026: Voice Agents and High-Stakes Trust
Voice is becoming one of the fastest paths for AI to do real work, especially in regulated environments where accuracy and compliance matter. In this episode...
- 54
Dec 23, 2025 · 22m E997
Big Ideas 2026: The Enterprise Orchestration Layer
AI is becoming the orchestration layer inside the enterprise. In this episode of Big Ideas 2026, we explore the shift from isolated AI copilots to coordinate...
- 55
Dec 22, 2025 · 14m E996
Big Ideas 2026: The Agentic Interface
AI is moving from chat to action. In this episode of Big Ideas 2026, we unpack three shifts shaping what comes next for AI products. The change is not just s...
- 56
Dec 19, 2025 · 45m E995
The Rise, Fall & Reset of The Fintech Industry
Fintech went from a full-blown surge to a near standstill in just two years. At its peak, about 25 percent of all venture dollars were pouring into the categ...
- 57
Dec 18, 2025 · 1h 2m E994
Do Revenue and Margins Still Matter in AI?
In this episode, we’re sharing a conversation with David George, General Partner at a16z on the firm’s growth investing team. David has been involved in back...
- 58
Dec 17, 2025 · 59m E993
The Crime Crisis In America and How Technology Fixes It
What if America tried to eliminate crime instead of just reacting to it? Not with slogans, but with staffing, technology, and strategy scaled to the problem....
- 59
Dec 16, 2025 · 52m E992
Ryo Lu (Cursor): AI Turns Designers to Developers
Ryo Lu spent years watching his designs die in meetings. Then he discovered the tool that lets designers ship code at the speed of thought: Cursor, the compa...
- 60
Dec 15, 2025 · 1h 32m E991
Dwarkesh and Ilya Sutskever on What Comes After Scaling
AI models feel smarter than their real-world impact. They ace benchmarks, yet still struggle with reliability, strange bugs, and shallow generalization. Why...
- 61
Dec 12, 2025 · 1h 2m E990
AI Eats the World: Benedict Evans on the Next Platform Shift
AI is reshaping the tech landscape, but a big question remains: is this just another platform shift, or something closer to electricity or computing in scale...
- 62
Dec 10, 2025 · 57m E988
How the Best CEOs Delegate
Jonathan Swanson has built two rare successes: Thumbtack, the home-services marketplace, and Athena, the fast-growing platform that pairs ambitious people wi...
- 63
Dec 9, 2025 · 37m E987
The $3 Trillion AI Coding Opportunity
Originally published on the a16z Infra podcast. We're resurfacing it here for our main feed audience. AI coding is already actively changing how software get...
- 64
Dec 8, 2025 · 30m E986
The 80-Year Bet: Why Naveen Rao Is Rebuilding the Computer from Scratch
Naveen Rao is cofounder and CEO of Unconventional AI, an AI chip startup building analog computing systems designed specifically for intelligence. Previously...
- 65
Dec 5, 2025 · 1h 1m E985
What Comes After ChatGPT? The Mother of ImageNet Predicts The Future
Fei-Fei Li is a Stanford professor, co-director of Stanford Institute for Human-Centered Artificial Intelligence, and co-founder of World Labs. She created I...
- 66
Dec 4, 2025 · 50m E984
How AI Created the Fastest Product Cycle in History
Recently, a16z General Partner Anish Acharya joined Ollie Forsyth on NEW ECONOMIES. They talked about why consumer tech is surging again, how AI is enabling...
- 67
Dec 3, 2025 · 51m E983
Why AI Moats Still Matter (And How They've Changed)
a16z General Partners David Haber, Alex Rampell, and Erik Torenberg discuss why 19 out of 20 AI startups building the same thing will die - and why the survi...
- 68
Dec 2, 2025 · 1h 10m E982
How To Lead | Ben Horowitz on My First Million
A16Z co-founder Ben Horowitz joins Shaan Puri and Sam Parr on My First Million to talk about how to be a great leader. Resources: Follow Ben on X: https://x....
- 69
Dec 1, 2025 · 58m E981
The $700 Billion AI Productivity Problem No One's Talking About
Russ Fradin sold his first company for $300M. He’s back in the arena with Larridin, helping companies measure just how successful their AI actually is. In th...
- 70
Nov 28, 2025 · 53m E980
How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning
In this episode, a16z GP Martin Casado sits down with Sherwin Wu, Head of Engineering for the OpenAI Platform, to break down how OpenAI organizes its platfor...
- 71
Nov 27, 2025 · 46m E979
Ben Horowitz: Why Open Source AI Will Determine America's Future
Ben Horowitz reveals why the US already lost the AI culture war to China—and it wasn't the technology that failed. While Biden's team played Manhattan Projec...
- 72
Nov 26, 2025 · 59m E978
The Secret Marketing Strategy That Built a16z: From Zero to Legendary VC Firm
Marc Andreessen and Ben Horowitz sit down with Margit Wennmachers—the woman who turned two unknown entrepreneurs with $300 million and zero investing track r...
- 73
Nov 25, 2025 · 34m E977
How Marc Andreessen Actually Uses AI
Half a billion people can access the world’s best AI on their phone. So why are most using it to write emails while only some are using it to build empires?...
- 74
Nov 24, 2025 · 1h E976
The 2045 Superintelligence Timeline: Epoch AI’s Data-Driven Forecast
Epoch AI researchers reveal why Anthropic might beat everyone to the first gigawatt datacenter, why AI could solve the Riemann hypothesis in 5 years, and wha...
- 75
Nov 21, 2025 · 1h 5m E975
Robinhood CEO: Making Everyone An Owner
Vlad Tenev built Robinhood by breaking every rule Wall Street wrote: zero commissions when competitors charged $10, mobile-first when "serious" investors dem...
- 76
Nov 20, 2025 · 43m E974
Can Community Banks Survive the Next SVB? | ModernFi CEO Paolo Bertolotti and Former Comptroller Gene Ludwig
The former bank regulator who invented deposit networks just revealed why SVB's collapse was inevitable—and why the solution that could have saved them is fi...
- 77
Nov 19, 2025 · 1h 16m E973
Ben Horowitz & Marc Andreessen: Why Silicon Valley Turned Against Defense (And How We’re Fixing It)
Palmer Luckey got fired from Meta for backing the wrong candidate—now he's the hero saving American defense, and that shift tells you everything about how fa...
- 78
Nov 17, 2025 · 1h 10m E972
Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering
Emmett Shear, founder of Twitch and former OpenAI interim CEO, challenges the fundamental assumptions driving AGI development. In this conversation with Erik...
- 79
Nov 14, 2025 · 1h 2m E970
Can America Win The AI Biotech Race Against China? | Lada Nuzhna & Elliot Hershberg
Two venture capitalists dissect why biotech burns billions while China runs trials in weeks—and why the next Genentech won't look anything like the last one....
- 80
Nov 13, 2025 · 44m E969
The Frontier of Spatial Intelligence with Fei-Fei Li
Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, they have long been laying the groundwo...